Efavirenz, >=98% (HPLC)

Code: SML0536-10MG D2-231

Application

Efavirenz has been used:to assess its anti-porcine endogenous retrovirus (PERV) activityin cytotoxicity assayto investigate the solute-solvent effects of efaviren...


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Your Price
€156.40 10MG
€192.37 inc. VAT

Application

Efavirenz has been used:to assess its anti-porcine endogenous retrovirus (PERV) activityin cytotoxicity assayto investigate the solute-solvent effects of efavirenz by means combined time-dependent density functional theory (TD-DFT) and spectroscopic calculations

Biochem/physiol Actions

Efavirenz is a nonnucleoside reverse transcriptase inhibitor (NNRTI). It is an anti-HIV drug, commonly used in combination therapy for AIDs treatment. It is part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

General description

Efavirenz, commercially known as Sustiva is a polycyclic aromatic hydrocarbon with benzene and oxazinan-2-one chromophores.

Legal Information

Sustiva is a trademark of E. I. du Pont de Nemours and Company

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyXPOQHMRABVBWPR-ZDUSSCGKSA-N
InChI1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1
optical activity[α]/D -90 to -100°, c = 1 in methanol
Quality Level100
SMILES stringClC1=CC=C2C([C@@](C#CC3CC3)(C(F)(F)F)OC(N2)=O)=C1
solubilityDMSO: 15 mg/mL, clear
storage temp.−20°C
Cas Number154598-52-4
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