Ritonavir, >=98% (HPLC)

Code: SML0491-10MG D2-231

Application

Ritonavir has been used:as a human immunodeficiency virus (HIV) protease inhibitor to study its effects on placental endocrine functionas an HIV protease inhibito...


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€88.80 10MG
€109.22 inc. VAT
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Application

Ritonavir has been used:as a human immunodeficiency virus (HIV) protease inhibitor to study its effects on placental endocrine functionas an HIV protease inhibitor to study its effects on reduction of tetrazolium dye in human embryonic kidney cellsas an organicaniontransportingpolypeptide (OATP) inhibitor to study its effect on hepatic uptake of bergapten and imperatorin

Biochem/physiol Actions

Ritonavir is an HIV protease inhibitor now used frequently as a booster of other protease inhbitors. Ritonavir inhibits cytochrome P450-3A4 (CYP3A4), a liver enzyme that normally metabolizes protease inhibitors. It has also been investigated as a possible anti-cancer agent.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyNCDNCNXCDXHOMX-XGKFQTDJSA-N
InChI1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1
Quality Level100
SMILES stringO=C(OCC1=CN=CS1)N[C@H]([C@@H](O)C[C@@H](NC([C@@H](NC(N(CC2=CSC(C(C)C)=N2)C)=O)C(C)C)=O)CC3=CC=CC=C3)CC4=CC=CC=C4
solubilityDMSO: 10 mg/mL (clear solution, warmed)
storage temp.room temp
Cas Number155213-67-5
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