Ro 61-8048, >=98% (HPLC)

Code: SML0233-5MG D2-231

Application

Ro 61-8048 has been used as a kynurenine3-monooxygenase (KMO) inhibitor to study its effects on nicotinamideadenine dinucleotide (NAD+) concentration i...


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€124.30 5MG
€152.89 inc. VAT
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Application

Ro 61-8048 has been used as a kynurenine3-monooxygenase (KMO) inhibitor to study its effects on nicotinamideadenine dinucleotide (NAD+) concentration in hepatocytes of mice.

Biochem/physiol Actions

Ro 61-8048 is an inhibitor of kynurenine 3-monooxygenase (KMO) that increases kynurenic acid levels and reduces extracellular glutamate in the brain.

Inhibition of kynurenine 3-hydroxylase by Ro 61-8048 reduces the episodes of dystonia and dyskinesias induced by decreased levels of kynurenic acid.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorfaintly yellow to yellow
formpowder
InChI keyNDPBMCKQJOZAQX-UHFFFAOYSA-N
InChI1S/C17H15N3O6S2/c1-25-15-7-6-13(9-16(15)26-2)28(23,24)19-17-18-14(10-27-17)11-4-3-5-12(8-11)20(21)22/h3-10H,1-2H3,(H,18,19)
Quality Level100
SMILES stringCOc1ccc(cc1OC)S(=O)(=O)Nc2nc(cs2)-c3cccc(c3)[N+]([O-])=O
solubilityDMSO: ≥15 mg/mL
storage temp.2-8°C
Cas Number199666-03-0
This product has met the following criteria to qualify for the following awards:



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