Fluocinonide, >=98% (HPLC)

Code: SML0099-10MG D2-231

Biochem/physiol Actions

Flucinonide is a fluorinated glucocorticid that is used as a topical anti-inflammatory agent. Recently, flucinonide and other fluorinated glucocortico...


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€139.80 10MG
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Biochem/physiol Actions

Flucinonide is a fluorinated glucocorticid that is used as a topical anti-inflammatory agent. Recently, flucinonide and other fluorinated glucocorticolids were identified as smoothend agonists. Flucinonide induces expression of Gli-reporter luciferase in Shh-LIGHT2 cells.

Fluocinonide has been used to study its effect on T-cell proliferation.

Fluocinonide is shown to be effective in the treatment of atopic dermatitis and oral lichen planus (OLP).

Packaging

10, 50 mg in glass bottle

assay≥98% (HPLC)
colorwhite to tan
formpowder
Gene Informationhuman ... NR3C1(2908)
InChI keyWJOHZNCJWYWUJD-IUGZLZTKSA-N
InChI1S/C26H32F2O7/c1-13(29)33-12-20(32)26-21(34-22(2,3)35-26)10-15-16-9-18(27)17-8-14(30)6-7-23(17,4)25(16,28)19(31)11-24(15,26)5/h6-8,15-16,18-19,21,31H,9-12H2,1-5H3/t15-,16-,18-,19-,21+,23-,24-,25-,26+/m0/s1
optical activity[α]/D +75 to +90°, c = 1 in dichloromethane
Quality Level100
SMILES stringCC(=O)OCC(=O)[C@@]12OC(C)(C)O[C@@H]1C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]23C
solubilityDMSO: ≥19 mg/mL
storage temp.2-8°C
Cas Number356-12-7
Hazard Class6.1
Un Number2811
Pack GroupII
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