Tubastatin A hydrochloride, >=98% (HPLC)

Code: SML0044-5MG D2-231

Application

Tubastatin A hydrochloride may be used in HDAC6-mediated cell signaling studies.

Biochem/physiol Actions

Tubastatin A increases the t...


read more

Your Price
€219.50 5MG
€269.99 inc. VAT
REQUEST

Application

Tubastatin A hydrochloride may be used in HDAC6-mediated cell signaling studies.

Biochem/physiol Actions

Tubastatin A increases the total numbers of mitochondria and restores the number of moving mitochondria in DRG neurons. It reverses the axonal loss in peripheral neurons in mouse model of Charcot-Marie-Tooth disease. Tubastatin A inhibits the deacetylation of α-tubulin in murine myoblasts.

Tubastatin A is a very selective HDAC6 inhibitor with an IC50 of 4 nM and 100 to over 1000-fold selectivity for HDAC6 over other HDAC classes.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to tan
formpowder
InChI keyLJTSJTWIMOGKRJ-UHFFFAOYSA-N
InChI1S/C20H21N3O2.ClH/c1-22-11-10-19-17(13-22)16-4-2-3-5-18(16)23(19)12-14-6-8-15(9-7-14)20(24)21-25;/h2-9,25H,10-13H2,1H3,(H,21,24);1H
Quality Level100
shipped inwet ice
SMILES stringO=C(NO)C1=CC=C(CN2C3=C(C=CC=C3)C4=C2CCN(C)C4)C=C1.Cl
solubilityDMSO: ≥10 mg/mL
storage temp.−20°C
This product has met the following criteria to qualify for the following awards:



PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN

GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.