Application

Fluvastatin sodium hydrate has been used:to examine its effect on β -glucan-induced training on immunityto investigate the effect of statins on the number ofuncoupling protein 1 (UCP1)⁺cellsto determine its effect on insulin degrading enzyme (IDE) secretion from astrocytesto treat and study its effect on human umbilical vein endothelial cells (HUVECs)in vitro

Fluvastatin sodium hydrate has been used:to test its anti-hepatitis C virus (HCV) activityas a cholesterol inhibitorto study its effects on β-glucan-induced monocyte immune training

Biochem/physiol Actions

Fluvastatin has antifungal activity.

Fluvastatin is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin is antilipemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Packaging

10, 50 mg in glass bottle