SMER3, >=98% (HPLC)

Code: S7826-5MG D2-231

Application

SMER3 may be used in cell signaling studies.

Biochem/physiol Actions

Small molecule enhancer of rapamycin (SMER); specific inhibitor ...


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€112.84 5MG
€138.79 inc. VAT
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Application

SMER3 may be used in cell signaling studies.

Biochem/physiol Actions

Small molecule enhancer of rapamycin (SMER); specific inhibitor of Ubiquitin E3 ligase.

Inhibition of SCFMet30 by SMER3 blocks the ubiquitination of Met4 and activates the Met4-containing transcription complex. The induction of MET-genes results in cell cycle arrest and reduced cell proliferation.1

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
coloryellow
formpowder
InChI keySFSSAKVWCKFRHE-UHFFFAOYSA-N
InChI1S/C11H4N4O2/c16-9-6-4-2-1-3-5(6)7-8(9)13-11-10(12-7)14-17-15-11/h1-4H
Quality Level100
SMILES stringO=C1c2ccccc2-c3nc4nonc4nc13
solubilityDMSO: ≥30 mg/mL
storage temp.2-8°C
Cas Number67200-34-4
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