SCH-442416, >=98% (HPLC)

Code: S6451-5MG D2-231

Application

SCH-442416 has been used:as a selective adenosine A2A antagonist to study its effects on cyclic adenosine monophosphate (cAMP) production in T/C-28a2 chondrocytes...


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Your Price
€119.05 5MG
€146.43 inc. VAT

Application

SCH-442416 has been used:as a selective adenosine A2A antagonist to study its effects on cyclic adenosine monophosphate (cAMP) production in T/C-28a2 chondrocytes or hFOB 1.19 osteoblastsas a presynaptic A2A receptor antagonists to study its effects on receptor blockade on δ9-Tetrahydrocannabinol (THC) self-administration in squirrel monkeys as a presynaptic A2A receptor antagonists to study its effects on cocaine-induced locomotion and cocaine-seeking in mice

Biochem/physiol Actions

SCH-442416 potent and selective Adenosine A2a antagonist. SCH-442416 is >10,000-fold selective for A2a compared to other adensosine receptors.

Features and Benefits

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorlight tan to tan
formpowder
InChI keyAEULVFLPCJOBCE-UHFFFAOYSA-N
InChI1S/C20H19N7O2/c1-28-14-8-6-13(7-9-14)4-2-10-26-18-15(12-22-26)19-23-17(16-5-3-11-29-16)25-27(19)20(21)24-18/h3,5-9,11-12H,2,4,10H2,1H3,(H2,21,24)
Quality Level100
SMILES stringCOc1ccc(CCCn2ncc3c2nc(N)n4nc(nc34)-c5ccco5)cc1
solubilityDMSO: ≥20 mg/mL
storage conditiondesiccated
storage temp.2-8°C
Cas Number316173-57-6
This product has met the following criteria to qualify for the following awards:



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