Etidronate disodium hydrate, >=97% (NMR), solid

Code: P5248-10MG D2-231

Application

Etidronate disodium hydrate has been used in the synthesis of bisphosphonate derivatives of adenosine triphosphate (ATP)by T4 RNA ligase. It has also been sued to...


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€154.30 10MG
€189.79 inc. VAT
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Application

Etidronate disodium hydrate has been used in the synthesis of bisphosphonate derivatives of adenosine triphosphate (ATP)by T4 RNA ligase. It has also been sued to inhibit human farnesyl diphosphate synthase (FDPS).

Biochem/physiol Actions

Bisphosphonate antiresorptive agent. Less potent inhibitor of farnesyl diphosphate synthase (IC50 = 80 µM) as compared to the nitrogen containing bisphosphonates

Etidronate helps to guard chronic ocular hypertension prompted retinal oxidative stress. It stimulates the development of retinal ganglion cells through insulin-like growth factor 1 (IGF-1) signaling pathway. It may possess neuroprotective effects in in vivo and in vitro rat model of glaucoma. Etidronate belongs to bisphosphonates.

Packaging

10, 100 mg in glass bottle

assay≥97% (NMR)
colorwhite
formsolid
InChI keyGWBBVOVXJZATQQ-UHFFFAOYSA-L
InChI1S/C2H8O7P2.2Na/c1-2(3,10(4,5)6)11(7,8)9;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-2
mp>300 °C
Quality Level100
SMILES string[Na+].[Na+].CC(O)(P(O)([O-])=O)P(O)([O-])=O
solubilityH2O: ≥10 mg/mL
storage temp.2-8°C
Cas Number7414-83-7
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