Name: Penitrem A, >=95% (HPLC and TLC)
Brand: SIGMA-ALDRICH
SKU: P3053-1MG
Price: 371.80 EUR

Application

Penitrem A has been used as Ca²⁺-Activated K⁺ (BK) channel blocker to study its effect on BK current in bag cell neurons.

Biochem/physiol Actions

Penitrem A intoxication causes ataxia, polypnea, and sustained tremors and may lead to seizures and death. Penitrem A affects the central and peripheral nervous system. It impairs the GABAergic neurotransmission in the cerebellum.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Other Notes

Originally isolated from Penicillium palitans

Packaging

1, 5 mg in glass bottle

assay	≥95% (HPLC and TLC)
form	powder
InChI key	JDUWHZOLEDOQSR-JKPSMKLGSA-N
InChI	1S/C37H44ClNO6/c1-15(2)28-27(40)31-37(45-31)23(43-28)9-10-33(6)34(7)18(8-11-35(33,37)41)29-25-24-21(39-30(25)34)14-20(38)17-12-16(3)19-13-22(32(4,5)44-29)36(19,42)26(17)24/h14,18-19,22-23,27-29,31,39-42H,1,3,8-13H2,2,4-7H3/t18-,19+,22+,23-,27-,28+,29-,31+,33+,34+,35-,36+,37-/m0/s1
Quality Level	200
SMILES string	[H][C@]12CC[C@@]3(C)[C@@](O)(CC[C@@]4([H])[C@]5([H])OC(C)(C)[C@@]6([H])C[C@]7([H])C(=C)Cc8c(Cl)cc9[nH]c(c5c9c8[C@]67O)[C@]34C)[C@]1O[C@]([H])[C@@H](O)[C@H](O2)C(C)=C
storage temp.	2-8°C

Safety Data Sheet for P3053-1MG

Cas Number	12627-35-9
Hazard Class	6.1
Un Number	2811
Pack Group	II

This product has met the following criteria to qualify for the following awards:

Penitrem A, >=95% (HPLC and TLC)

ABOUT US

CUSTOMER SUPPORT

TERMS & POLICIES

CALL US

PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN

GUEST CHECKOUT