Application
Nicotinic acid adenine dinucleotide phosphate sodium salt has been used for agonist injection into unfertilized eggs and embryos.
Biochem/physiol Actions
Potent activator of intracellular Ca2+ release via an IP3 and cyclic ADP ribose-independent mechanism.
General description
NAADP induces Ca2+release from the eggs of sea urchin, when injected into the cell. It can be enzymatically produced from nicotinamide adenine dinucleotide phosphate (β-NADP) with the help of ADP-ribosyl cyclase.
Other Notes
Note: Should not be confused with nicotinamide adenine dinucleotide phosphate (NADP).
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. N5655.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Packaging
10, 25 mg in poly bottle
Preparation Note
Enzymatically prepared analog of β-NADP+.
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