(-)-Nicotine hemisulfate salt, >=95% (TLC), approx.40 % (w/v) in H2O (based on free base)

Code: N1019-100ML D2-231

Application

(−)-Nicotine hemisulfate salt has been used to study the influence of nicotine on the severity of choroidal neovascularization (CNV). It also has been used as a n...


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€128.36 100ML
€157.88 inc. VAT
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Application

(−)-Nicotine hemisulfate salt has been used to study the influence of nicotine on the severity of choroidal neovascularization (CNV). It also has been used as a natural nectar alkaloid to study the effect of self-medication in bumblebees.

Biochem/physiol Actions

Prototype nicotinic acetylcholine receptor agonist; naturally occurring isomer.

Caution

Shelf-life of the solution as supplied is at least six years when stored at room temperature.

General description

Nicotine is found in the leaves of Nicotiana species. It binds to nicotinic acetylcholine receptors and inhibits endogenous neurotransmitters. Nicotine is associated with lung cancer development and reduces the efficiency of chemotherapeutic agents. It is used to treat Alzheimer′s and Parkinson′s disease.

Packaging

25, 100 mL in glass bottle

Quality

Mixture of nicotine base and nicotine sulfate.

assay≥95% (TLC)
colordark brown
concentration~35 % (w/v) in H2O (based on free base)
formliquid
Gene Informationhuman ... CHRNA4(1137), CHRNB2(1141)
InChI keyIECQULMJVNSKDB-RCWTXCDDSA-N
InChI1S/2C10H14N2.H2O4S/c2*1-12-7-3-5-10(12)9-4-2-6-11-8-9;1-5(2,3)4/h2*2,4,6,8,10H,3,5,7H2,1H3;(H2,1,2,3,4)/t2*10-;/m00./s1
Quality Level100
SMILES stringOS(O)(=O)=O.CN1CCC[C@H]1c2cccnc2.CN3CCC[C@H]3c4cccnc4
Cas Number65-30-5
Hazard Class6.1
Un Number1658
Pack GroupII
This product has met the following criteria to qualify for the following awards:



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