Loratadine, >=98% (HPLC), powder

Code: L9664-10MG D2-231

Biochem/physiol Actions

Loratadine is a non-sedating histamine H1-receptor antagonist. Shown to inhibit the two-pore domain potassium channel K2P18.1 (also called TRESK or KC...


read more

Your Price
€292.00 10MG
€359.16 inc. VAT
REQUEST

Biochem/physiol Actions

Loratadine is a non-sedating histamine H1-receptor antagonist. Shown to inhibit the two-pore domain potassium channel K2P18.1 (also called TRESK or KCNK18).

Non-sedating histamine H1-receptor antagonist.

Features and Benefits

This compound was developed by Schering Plough. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. L9664.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

assay≥98% (HPLC)
colorwhite
formpowder
Gene Informationhuman ... CYP3A4(1576), HRH1(3269), KCNH1(3756), KCNH2(3757), PTAFR(5724)rat ... Hrh1(24448)
InChI keyJCCNYMKQOSZNPW-UHFFFAOYSA-N
InChI1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3
originatorSchering Plough
Quality Level200
SMILES stringCCOC(=O)N1CCC(CC1)=C2/c3ccc(Cl)cc3CCc4cccnc24
solubilityDMSO: soluble 50 mg/mL, H2O: insoluble
storage temp.2-8°C
Cas Number79794-75-5
This product has met the following criteria to qualify for the following awards:



PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN

GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.