Icilin, >=97% (HPLC), solid

Code: I9532-10MG D2-231

Application

Icilin has been used as cooling agent in anterior ventromedial preoptic area (VMPO) neurons.

Biochem/physiol Actions

Icilin is a pote...


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€221.60 10MG
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Application

Icilin has been used as cooling agent in anterior ventromedial preoptic area (VMPO) neurons.

Biochem/physiol Actions

Icilin is a potent agonist at the CMR1 cold- and menthol-sensitive receptor.

General description

Icilin is a synthetic cooling agent and modulates human transient receptor potential cation channel (TRPA1). Icilin inhibits transient receptor potential cation channel subfamily M member 8 (TRPM8) and modulates calcium release. Icilin also suppresses transient receptor potential vanilloid subtype 3 (TRPV3).

Packaging

10, 50 mg in glass bottle

assay≥97% (HPLC)
coloryellow
formsolid
InChI keyRCEFMOGVOYEGJN-UHFFFAOYSA-N
InChI1S/C16H13N3O4/c20-15-7-2-1-6-14(15)18-9-8-13(17-16(18)21)11-4-3-5-12(10-11)19(22)23/h1-8,10,20H,9H2,(H,17,21)
Quality Level100
SMILES stringOc1ccccc1N2CC=C(NC2=O)c3cccc(c3)[N+]([O-])=O
solubilityDMSO: 15 mg/mL
Cas Number36945-98-9
This product has met the following criteria to qualify for the following awards:



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