GW0742, >=98% (HPLC), solid

Code: G3295-5MG D2-231

Biochem/physiol Actions

GW0742 is a highly selective PPARδ agonist. EC50 = 1 nM vs 1 µM and 2 µM for PPARα and PPARγ, respectively.

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€707.04 5MG
€869.66 inc. VAT

Biochem/physiol Actions

GW0742 is a highly selective PPARδ agonist. EC50 = 1 nM vs 1 µM and 2 µM for PPARα and PPARγ, respectively.

Features and Benefits

This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from GlaxoSmithKline

Packaging

1, 5 mg in glass bottle

assay≥98% (HPLC)
colorwhite
formpowder
Gene Informationhuman ... PPARA(5465), PPARD(5467), PPARG(5468)
InChI keyHWVNEWGKWRGSRK-UHFFFAOYSA-N
InChI1S/C21H17F4NO3S2/c1-11-7-14(4-6-17(11)29-9-19(27)28)30-10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)
mp134.5-135.5 °C
originatorGlaxoSmithKline
Quality Level100
SMILES stringCc1cc(SCc2sc(nc2C)-c3ccc(c(F)c3)C(F)(F)F)ccc1OCC(O)=O
solubilityDMSO: >5 mg/mL, H2O: insoluble
storage temp.2-8°C
Cas Number317318-84-6
This product has met the following criteria to qualify for the following awards:



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