G?? 6983, >=97%

Code: G1918-500UG D2-231

Application

GO6983 has been used as a protein kinase C (PKC) inhibitor to study its effects on the nuclear import. It has also been used as a supplement in Fc medium to cultu...


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€116.00 500UG
€142.68 inc. VAT
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Application

GO6983 has been used as a protein kinase C (PKC) inhibitor to study its effects on the nuclear import. It has also been used as a supplement in Fc medium to culture mouse embryonic stem (mES) cells on mitomycin C treated mouse embryonic fibroblasts (MEFs).

Biochem/physiol Actions

Protein kinase C (PKC) inhibitor that selectively inhibits several PKC isozymes (IC50 = 7 nM for PKCα and PKCβ; 6 nM for PKCγ; 10 nM for PKCδ; and 60 nM for PKCζ), but does not inhibit PKCµ (IC50 = 20 mM).

Packaging

500 µg in glass bottle

1 mg in glass bottle

assay≥97%
formpowder
InChI keyLLJJDLHGZUOMQP-UHFFFAOYSA-N
InChI1S/C26H26N4O3/c1-29(2)11-6-12-30-15-20(18-13-16(33-3)9-10-22(18)30)24-23(25(31)28-26(24)32)19-14-27-21-8-5-4-7-17(19)21/h4-5,7-10,13-15,27H,6,11-12H2,1-3H3,(H,28,31,32)
Quality Level100
SMILES stringCOc1ccc2n(CCCN(C)C)cc(C3=C(C(=O)NC3=O)c4c[nH]c5ccccc45)c2c1
solubilityDMSO: 10 mg/mL, clear
storage temp.−20°C
Cas Number133053-19-7
This product has met the following criteria to qualify for the following awards:



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