Name: CA-074 methyl ester, >=99% (TLC), solid
Brand: SIGMA-ALDRICH
SKU: C5857-5MG
Price: 592.20 EUR
Availability: InStock

Application

CA-074 methyl ester has been used as cathepsin B inhibitor in cardiomyocytes, HeLa cells and human pancreatic cancer PANC-1 cells.

Biochem/physiol Actions

CA-074 methyl ester is a cell-permeable analog of CA-074. It is an inhibitor of cathepsin B especially the intracellular type. and undergoes intracellular transition into active CA-074 by the action of esterases. CA-074 methyl ester also inhibits cathepsin L.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

assay	≥99% (TLC)
biological source	synthetic (organic)
form	solid
InChI key	XGWSRLSPWIEMLQ-RQLZCWDZSA-N
InChI	1S/C19H31N3O6/c1-5-9-20-16(23)14-15(28-14)17(24)21-13(11(3)6-2)18(25)22-10-7-8-12(22)19(26)27-4/h11-15H,5-10H2,1-4H3,(H,20,23)(H,21,24)/t11?,12-,13-,14-,15-/m0/s1
Quality Level	100
SMILES string	CCCNC(=O)[C@H]1O[C@@H]1C(=O)N[C@@H](C(C)CC)C(=O)N2CCC[C@H]2C(=O)OC
storage temp.	−20°C

Safety Data Sheet for C5857-5MG

Cas Number

147859-80-1

This product has met the following criteria to qualify for the following awards:

CA-074 methyl ester, >=99% (TLC), solid

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