ARL 67156 trisodium salt hydrate, >=98% (HPLC), solid

Code: A265-25MG D2-231

Application

ARL 67156 trisodium salt hydrate has been used:to prevent ATP degradation during cerebrospinal fluid extractionas an ATPase inhibitor in ATP quantification assay ...


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€1,683.50 25MG
€2,070.71 inc. VAT
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Application

ARL 67156 trisodium salt hydrate has been used:to prevent ATP degradation during cerebrospinal fluid extractionas an ATPase inhibitor in ATP quantification assay for preventing ATP degradation in cytoplasm and mitochondrionas an ecto-ATPase inhibitor to treat cancer cells for ATP release assay

Biochem/physiol Actions

ARL 67156, a nucleotide/ATP analog is a competitive inhibitor of CD39. This ecto-ATPase inhibitor is presumed to be metabolically stable in biological studies due to its β,γ-dibromomethylene bridge.

assay≥98% (HPLC)
colorwhite to off-white
formsolid
Gene Informationhuman ... ENTPD2(954)
InChI keyUWMONIJVKGTUGE-OPKBHZIBSA-K
InChI1S/C15H24Br2N5O12P3.3Na.H2O/c1-3-21(4-2)12-9-13(19-6-18-12)22(7-20-9)14-11(24)10(23)8(33-14)5-32-37(30,31)34-36(28,29)15(16,17)35(25,26)27;;;;/h6-8,10-11,14,23-24H,3-5H2,1-2H3,(H,28,29)(H,30,31)(H2,25,26,27);;;;1H2/q;3*+1;/p-3/t8-,10-,11-,14-;;;;/m1..../s1
Quality Level100
SMILES stringO.[Na+].[Na+].[Na+].CCN(CC)c1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)C(Br)(Br)P([O-])([O-])=O)[C@@H](O)[C@H]3O
solubilityDMSO: insoluble, H2O: >20 mg/mL
storage temp.−20°C
Cas Number160928-38-1
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