Aphidicolin from Nigrospora sphaerica, >=98% (HPLC), powder

Code: A0781-5MG D2-231

Biochem/physiol Actions

Aphidicolin is an antibiotic, a potent antiviral and antimitotic agent and DNA polymerase inhibitor.

Caution

Estimated sh...


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€516.56 5MG
€635.37 inc. VAT
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Biochem/physiol Actions

Aphidicolin is an antibiotic, a potent antiviral and antimitotic agent and DNA polymerase inhibitor.

Caution

Estimated shelf-life is two years. For optimal stability, it should be protected from light and stored desiccated.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

1, 5, 10 mg in glass bottle

antibiotic activity spectrumneoplastics, viruses
assay≥98% (HPLC)
colorwhite
formpowder
Gene Informationhuman ... POLA1(5422), POLD1(5424), POLG(5428)
InChI keyNOFOAYPPHIUXJR-APNQCZIXSA-N
InChI1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1
mode of actionDNA synthesis | interferes
mp227-233 °C (lit.)
optical activity[α]27/D +12°, c = 1 in methanol(lit.)
Quality Level300
SMILES string[H][C@@]12CC[C@@]3([H])[C@](C)(CO)[C@H](O)CC[C@]3(C)[C@]14CC[C@](O)(CO)[C@]([H])(C2)C4
solubilityethanol: 1 mg/mL (stable at least a week at 4°C.), methanol: 10 mg/mL, H2O: insoluble, DMSO: 10 mg/mL (stable at least six weeks at −20°C.)
storage temp.2-8°C
Cas Number38966-21-1
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