Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
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General description
Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase and it participates in the repair of DNA double-strand breaks. ATM is expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, spleen, thymus, testis, ovary, small intestine, colon and leukocytes. Increased ATM protein expression was reported in prostatic intraepithelial neoplasias (PINs) and some prostate cancer. ATM mutation has also been identified in mantle cell lymphoma, gastric cancer, lung adenocarcinoma, and breast cancer.
Immunogen
Synthetic peptide derived from human ATM protein.
Physical form
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
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