Anti-phospho-mTOR (pSer2448) antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Application

Anti-phospho-mTOR (pSer2448) antibody has been used in western blotting.

Biochem/physiol Actions

The mechanistic/mammalian target of rapamycin (mTOR) controls protein translation, cell growth, survival, invasion and metabolism. It acts as an intracellular signalling regulator, which links the extracellular events to the intracellular process. mTOR also acts on the protein synthesis machinery.

Disclaimer

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Features and Benefits

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General description

The mechanistic/mammalian target of rapamycin (mTOR) is a serine/threonine kinase. It is a member of the phosphatidylinositide 3-kinases (PI 3-kinases or PI3Ks) family. It is mapped to human chromosome 1p36.22.

Immunogen

The antiserum was produced against synthesized peptide derived from human mTOR around the phosphorylation site of Ser2448.Immunogen Range: 2415-2464

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.