ANTI-PROTEASE-7 ANTIBODY PRODUCED IN RA

Application

Anti-Protease-7 antibody specifically recognizes Protease-7 from E. coli and Shigella flexneri and does not cross react with Proteus mirabilis. The antibody may be used in various immunochemical techniques including Immunoblotting (doublet ~35 kDa).

Disclaimer

This product is for R&D use only, not for drug, household, or other uses.

General description

E. coli Protease-7, also known as Omptin (ompT) or Outer membrane protein 3B, belongs to the omptin family of outer membrane proteases found in several Gram-negative bacteria of the Enterobacteriaceae family. Omptins are unique proteases combining features of both serine and aspartate proteases activity. Several group members may also have cysteine protease and metalloproteases activities, all share a conserved active site. The enzyme proteolytic activity is dependent on the interaction with the lipid A region of the lipopolysaccharide (LPS).

Immunogen

Synthetic peptide corresponding to human N-terminal region E.coli Protease7, conjugated to KLH

Physical form

Supplied as a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide as a preservative.