ANTI-HUMAN IGE-PEROXIDASE ANTIBODY MOU

Code: SAB4200755-1VL D2-231

Application

Anti-Human IgE-Peroxidase antibody has been used in enzyme linked immunosorbent assay (ELISA).

Biochem/physiol Actions

IgE plays a cr...


 Read more

Your Price
€415.00 EACH
€510.45 inc. VAT

Application

Anti-Human IgE-Peroxidase antibody has been used in enzyme linked immunosorbent assay (ELISA).

Biochem/physiol Actions

IgE plays a critical role in allergic reactions and host protection from parasites. During an allergic reaction such as atopic eczema, extrinsic asthma or hay fever, fungal and parasitic infection, atopic disease, or primary immunodeficiency the serum IgE levels can be induced up to 5-fold. IgE specifically and reversibly binds to the membrane receptor Fc-epsilon receptors (FcεR) type I on the surface of basophils, eosinophils, and mast cells. This binding activates the release of histamine, leukotrienes, and other mediators responsible for hypersensitivity. The recognition and isolation of allergen-specific IgE can lead to progress in understanding of pathophysiologic mechanisms underlying IgE-associated allergic disorders.

General description

Monoclonal Anti-Human IgE (mouse IgG2b isotype) is derived from the GE-1 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from a mouse immunized with purified human IgE myeloma protein. IgE (Immunoglobulin E) is the least abundant immunoglobulin isotype. IgE is produced by plasma cells and is highly functional in the lung, skin, and mucous membranes. Normal levels of IgE in serum are less than 1 µmL.

Immunogen

Purified human IgE

Other Notes

This product is for R&D use only, not for drug, household, or other uses.

Physical form

Supplied as a lyophilized powder.

Specificity

Monoclonal Anti-Human IgE specifically recognizes Human IgE. The antibody shows no cross-reactivity with human IgG1, IgG2, IgG3, IgG4, IgA, and IgM.

antibody formpurified from hybridoma cell culture
antibody product typeprimary antibodies
biological sourcemouse
cloneGE-1, monoclonal
conjugateperoxidase conjugate
formlyophilized powder
isotypeIgG2b
Quality Level200
shipped indry ice
species reactivityhuman
storage temp.−20°C
technique(s)ELISA: 1:20,000-1:30,000 using 5 µg/mL Human IgE myeloma for coating
This product has met the following criteria to qualify for the following awards:



HAVE AN ACCOUNT? LOGIN

GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.