Application

ANTI-SNAIL (N-TERM D24) antibody produced in rabbit has been used in Western Blotting.

Biochem/physiol Actions

Snail family transcriptional repressor 1 (SNAIL) acts as a repressor of genes associated with the epithelial phenotype like E-cadherin and increases the expression of genes linked with the mesenchymal phenotype. It has a role in epithelial-mesenchymal transition. The protein aids in G1 transition (early to late) in the cell cycle. SNAIL also modulates cell-matrix adhesion.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Snail family transcriptional repressor 1 (SNAIL) is a transcription factor and the gene encoding it is localized on human chromosome 20q13.13.

Physical form

Supplied in PBS with 0.09% (W/V) sodium azide