RABBIT ANTI-BETA-CATENIN ANTIBODY

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

The epitope recognized by PLA0230 maps to a region between residue 760 and 781 of human beta-catenin using the numbering given in entry NP_001895.1 (GeneID 1499).

Other Notes

Beta-catenin plays an integral role in the Wnt signaling pathway and is critical to morphogenic signaling and body axis specification. Beta-catenin exists in complexes with cadherins, transmembrane proteins that mediate cell adhesion. When Wnt-signaling proteins bind their receptors, beta-catenin is stabilized and accumulates in the cell. Translocation of stabilized beta-catenin allows its association with transcription factors and the activation of specific gene expression.

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide