RABBIT ANTI-BLM ANTIBODY

Code: PLA0029-100UL D2-231

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to b...


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Your Price
€484.00 100UL
€595.32 inc. VAT

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

The epitope recognized by PLA0029 maps to a region between residue 1325 and the C-terminus (residue 1417) of human Bloom Syndrome using the numbering given in entry NP_000048.1 (GeneID 641).

Other Notes

Bloom syndrome protein (BLM) is a RecQ DNA-helicase that plays a role in DNA replication and repair. Mutations and inactivation of BLM result in human syndromes characterized by dwarfism, infertility, erythema, learning disabilities, immune deficiency and predisposition to cancer. BLM has been shown to associate with the BRCA1-associated genome surveillance complex (BASC) which contains BRCA1, MSH2, MSH6, MLH1, ATM, PMS2 and the RAD50-MRE11-NBS1 protein complex.

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

accession no.NP_000048.1
antibody formaffinity purified immunoglobulin
antibody product typeprimary antibodies
biological sourcerabbit
Gene Informationrabbit ... BLM(641)
gradePowered by Bethyl Laboratories, Inc.
Quality Level100
shipped inwet ice
species reactivityhuman, mouse
storage temp.2-8°C
technique(s)immunoprecipitation (IP): 2-10 µg/mg, western blot: 1:1,000- 1:10,000
UniProt accession no.P54132
This product has met the following criteria to qualify for the following awards:



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