Analysis Note
ControlHuman serum and plasma
Application
Research CategoryApoptosis & Cancer
Research Sub CategoryApoptosis - Additional
Detect Albumin using this mouse monoclonal antibody, Anti-human Albumin Antibody, clone 8F6F9 validated for use in western blotting.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Human Albumin, also known as Serum albumin (ALB), is a member of the ALB/AFP/VDB family. Serum albumin is the main protein of plasma and has been shown to bind with water, Ca2+, Na+, K+, fatty acids, hormones, bilirubin and drugs. Human Albumin plays an important role in the regulation of the colloidal osmotic pressure of the blood. Additionally, Human Albumin has been shown to be the major zinc transporter in plasma, and typically binds about 80% of all plasma zinc. Mutations in ALB are implied to be the cause of familial dysalbuminemic hyperthyroxinemia (FDH), a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T4. Human Albumin is expressed primarily in plasma.
Immunogen
Human sera albumin
Physical form
Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Unpurified
Quality
Evaluated by Western Blotting in human serum and plasma.
Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected human Albumin in human serum and plasma.
Optimal working dilutions must be determined by end user.
Storage and Stability
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Target description
~50 and ~69 observed. Uncharacterized bands may appear in some lysate(s).
This product has met the following criteria to qualify for the following awards: