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Anti-Caspr; clone K65/35

Code: MABN69 D2-231

Analysis Note

ControlRat brain membrane tissue lysate


Research Sub CategorySignaling Neuroscience

Research CategoryNeuroscience...

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Analysis Note

ControlRat brain membrane tissue lysate


Research Sub CategorySignaling Neuroscience

Research CategoryNeuroscience

Immunohistochemistry Analysis: 1:300 dilution from a previous lot detected Caspr in rat cerebellum and rat hippocampus tissues.

Anti-Caspr Antibody, clone K65/35 is an antibody against Caspr for use in IH & WB.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Contactin-associated protein 1(Caspr) is a single-pass type I membrane protein belonging to the neurexin family and is comprised of one F5/8 type C domain, one fibrinogen C-terminal domain, two EGF-like domains, and four laminin G-like domains. Caspr is well documented for its interaction with contactin, an interaction that is crucial to the transport of Caspr to the plasma membrane, the mylination of glial cells, and the generation of axoglial junctions. Studies also suggest that Caspr may play a regulatory role in the cell surface expression of contactin and its targeting to different axonal domains. Expression of Caspr is largely observed in the brain, mainly in CNS myelinated nerve fibers within paranodal axoglial junctions.


Recombinant protein corresponding to rat Caspr.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Protein G

Format: Purified


Evaluated by Western Blot in rat brain membrane tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Caspr on 10 µg of rat brain membrane tissue lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~ 220 kDa observed

antibody formpurified immunoglobulin
antibody product typeprimary antibodies
biological sourcemouse
cloneK65/35, monoclonal
Gene Informationrat ... Cntnap1(84008)
NCBI accession no.NP_114450
Quality Level100
shipped inwet ice
species reactivity (predicted by homology)mouse (based on 100% sequence homology)
species reactivityrat
technique(s)western blot: suitable, immunohistochemistry: suitable
UniProt accession no.P97846
This product has met the following criteria: