Application
Research Sub CategoryIntegrins
Anti-Integrin β6 Antibody, clone CSβ6, azide free detects level of Integrin β6 & has been published & validated for use in FC, IP, IC, IH.
Research CategoryCell Structure
Immunohistochemistry (acetone fixation): Effective for Rabbit, rat, monkey, and human. Not effective for mouse tissue.
Immunocytochemistry: Effective for F6, HT-29, H441 cell lines (others not tested).
Flow cytometry: Effective for all species tested, including rabbit, rat, monkey, human, and mouse.
Immunoprecipitation
Optimal working dilutions must be determined by end user.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
beta 6 knockout mice have been immunized with recombinant secreted human alpaVbeta6.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Sterile-filtered liquid at 1 mg/mL in PBS, containing no preservatives.
Format: Purified
Specificity
Monoclonal antibody MAB2076Z, raised by immunizing beta6 knockout mice with recombinant secreted human alphavbeta6, is useful for flow cytometry and immunoprecipitation in all species tested, including mouse. It also works well for immunohistochemistry of acetone-fixed tissues in several species, including rat, rabbit, monkey, and human. The antibody does not work well for immunohistochemistry of mouse tissue. This antibody does not recognize the aV subunit and does not react with alphaV integrins other than alphavbeta6. Because the antibody is not effective in western blot, it is unknown whether the epitope recognized by the antibody localizes to the alphavbeta6 heterodimer or to the beta6 subunit only.
Storage and Stability
Maintain at 2-8°C.
This product has met the following criteria to qualify for the following awards: