INTEGRIN B3; MS X-100UG

Application

Detect Integrin β3 using this Anti-Integrin β3 Antibody, clone SAP validated for use in WB, IH, IH(P).

Immunohistochemistry (frozen and fixed tissue sections) including paraffin embedded sections. {See Van Belle et al 1999, original paper detailing the use in human, paraffin tissues}

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10333228.

Western blot: recognizes ~115kDa band in reduced

Optimal working dilutions must be determined by end user.

Immunogen

Membranes of freshly isolated human platelets.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Purified immunoglobulin. Liquid at 1 mg/mL in 0.02M phosphate buffer, 0.25M sodium chloride, pH 7.6, containing 0.1% sodium azide as a preservative.

Format: Purified

Specificity

Monoclonal antibody MAB2008 is specific for the beta-3 subunit of the vitronectin receptor (VNR)J, which is expressed on endothelial cells, platelets, melanoma, and glioma cells. The antibody is of high affinity.