Anti-Mouse IgG (Fc specific) F(ab)2 fragment antibody produced in goat, 2.0 mg/mL, affinity isolated antibody, buffered aqueous solution

Application

Anti-Mouse IgG (Fc specific) F(ab′)2 fragment antibody produced in goat has been used in CD117/Sca-1 fluorescence-activated cell sorting (FACS) analysis and to detect bound factor H in factor H binding assay.

Biochem/physiol Actions

Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond.It mainly helps in immune defense. It is a glycoprotein.IgG is a major class of immunoglobulin.Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3.

Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice .

Immunogen

Purified mouse IgG

Other Notes

Antibody adsorbed with bovine, equine and human serum proteins

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 0.05% sodium azide.

Preparation Note

Adsorbed to reduce background with bovine, equine, or human samples.Useful when trying to avoid background staining due to the presence of Fc receptors.