Application
Monoclonal Anti-Calmodulin antibody produced in mouse has been used in: enzyme-linked immunosorbent assay (ELISA)immunoblotdot blotimmunocytochemistryimmunoprecipitationimmunofluorescence
Biochem/physiol Actions
Calmodulin is a ubiquitous molecule which can bind up to 4 calcium ions, regulating and mediating a wide variety of biochemical processes.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Calmodulin is a highly conserved 17kDa calcium binding protein found in all eukaryotic cells. It is a multifunctional molecule. Monoclonal anti-Calmodulin (mouse IgG1 isotype) is derived from the 6D4 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with calmodulin, purified from Dictyostelium discoideum and conjugated to KLH.
Calmodulin belongs to a family of structurally homologous Ca2+-binding proteins. CALM1gene is located on human chromosome 14q32.11.
Immunogen
preparation of purified calmodulin from Dictyostelium discoideum conjugated to KLH.
Specificity
These antibodies are directed against different epitopes within the calmodulin molecule.
The antibody recognizes native and SDS-denatured calmodulin.
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