Anti-ZIC2

Biochem/physiol Actions

ZIC2 is a C2H2-type zinc finger protein that functions as a repressor of transcription and regulates the tissue specific expression of dopamine receptor D1. Expression of ZIC2 is important for the development of nervous system and extension of neurites. ZIC2 inhibits the signaling mediated by Wnt/β-catenin during embryonic development.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Synthetic peptide directed towards the C terminal region of human ZIC2

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: EPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGS