Analysis Note

ControlBALB3T3/A31 cell lysate

Application

Research CategoryCell Structure

Anti-Claudin-7 Antibody is an antibody against Claudin-7 for use in WB.

Research Sub CategoryECM Proteins

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Claudin-7 is a member of a family of claudins that are tight junction integral membrane proteins with four transmembrane domains and two extracellular loops. Claudin-7 has been shown to be under-expressed in invasive ductal carcinomas and colorectal carcinomas as compared to normal epithelial cells. Claudin-7 differs from other claudins because it has both structural and regulatory functions, regulating the expression of prostate specific antigen.

Immunogen

KLH-conjugated linear peptide corresponding to human Claudin-7.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Western Blot in BALB3T3/A31 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Claudin-7 in 10 µg of BALB3T3/A31 cell lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~22 kDa observed