Application

Immunocytochemistry Analysis: 10 µg/mL from a representative lot detected NOD4 in HeLa cells.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected NOD4 in HeLa cells.

Anti-NOD4 Antibody is an antibody against NOD4 for use in western blotting, ICC & immunofluorescence.

General description

Protein NLRC5, also known as Caterpiller protein 16.1 (CLR16.1) or Nucleotide-binding oligomerization domain protein 27 or Nucleotide-binding oligomerization domain protein 4, and encoded by the gene name NLRC5 or NOD4 or NOD27, may play an important role in regulating the type II interferon signaling pathway. NOD4 is expressed in spleen, thymus, lung, brain, tonsil, heart and prostate. NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.

Immunogen

KLH-conjugated synthetic peptide corresponding to the N-terminus of human NOD4.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Quality

Evaluated by Western Blotting in EL4 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected NOD4 in EL4 cell lysate.

Target description

~205 kDa observed. Uncharacterized bands may be observed in some lysate(s). Uniprot describes 6 isoforms produced by alternative splicing ranging between ~79 kDa and ~206 kDa