Anti-DMRT2

Application

Research Sub CategoryNuclear Receptors

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected DMRT2 in human kidney and rat testis tissue.

Research CategoryEpigenetics & Nuclear Function

Anti-DMRT2 Antibody is an antibody against DMRT2 for use in Western Blotting and Immunohistochemistry.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Doublesex- and mab-3-related transcription factor 2 is encoded by the DMRT2 gene in human and directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to its early epaxial enhancer element. In addition, it is also involved in somite develoment during embryogenesis. The human protein shares a DM DNA-binding domain with Drosophila ′doublesex′ (dsx) and C. elegans mab3 gene products involved in sex determination.

Immunogen

KLH-conjugated linear peptide corresponding to human DMRT2.

Other Notes

Concentration: Please refer to lot specific datasheet.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Western Blotting in human kidney tissue lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected DMRT2 in 10 µg of human kidney tissue lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~70 kDa observed