Anti-Ligand-dependent nuclear receptor-interacting factor 1

Application

This Anti-Ligand-dependent nuclear receptor-interacting factor 1 Antibody is validated for use in western blotting & ICC for the detection of Ligand-dependent nuclear receptor-interacting factor 1.

Research CategoryEpigenetics & Nuclear Function

Research Sub CategoryChromatin Biology

Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected Ligand-dependent nuclear receptor-interacting factor 1 in HeLa, A431, HepG2, and NIH/3T3 cells.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1), also known as RIF1, Receptor-interacting factor 1, and is encoded by the gene LRIF1/C1orf103/RIF1. The retinoic acid receptors (RARs) are ligand-dependent transcription factors that play critical roles in cell differentiation, embryonic development, and tumor suppression. RAR transcriptional activities are mediated by a growing family of nuclear receptor (NR) coregulators. Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is such a coregulator. Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is a repressor of ligand-induced transcriptional activity of retinoic receptor alpha. Ligand-dependent nuclear receptor-interacting factor 1 (LRIF1) is ubiquitously expressed in a wide variety of tissues and cells and localizes exclusively to the nucleus and specifically to the nuclear matrix.

Immunogen

KLH-conjugated linear peptide corresponding to a region near the C-terminus of human Ligand-dependent nuclear receptor-interacting factor 1.

Epitope: Near C-terminus

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Western Blotting in SH-SY5Y cell lysate.

Western Blotting Analysis: A 1:2,000 dilution of this antibody detected Ligand-dependent nuclear receptor-interacting factor 1 in 10 µg of SH-SY5Y cell lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~100 kDa observed