Anti-RIPK1

Application

Research CategoryApoptosis & Cancer

This Anti-RIPK1 Antibody is validated for use in Western Blotting_x000D_ and Immunohistochemistry for the detection of RIPK1.

Research Sub CategoryApoptosis - Additional

Immunohistochemistry Analysis (IHC): 2.5 µg/mL from a representative lot detected RIPK1 in mouse kidney tissue.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Receptor-interacting serine/threonine-protein kinase 1, also known as Cell death protein RIP or Receptor-interacting protein 1 (RIP-1) or Serine/threonine-protein kinase RIP, and encoded by the gene name RIPK1 or RIP or RIP1, contains 1 death domain and 1 protein kinase domain. RIPK1 is localized to the cytoplasm and plays an important role in a variety of cellular pathways including the NF-κB pathway and programmed necrotic cell death (necroptosis).

Immunogen

RIPK1 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human RIPK1.

Epitope: Near N-terminus

Other Notes

Concentration: Please refer to lot specific datasheet.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.

Quality

Evaluated by Western Blotting in rat kidney tissue lysate.

Western Blotting Analysis (WB): 1 µg/mL of this antibody detected RIPK1 in rat kidney tissue lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~75 kDa observed. Uncharacterized bands may be observed in some lysate(s).