Application

Detect ARG3.1 using this Anti-ARG3.1 Antibody validated for use in IH.

Research CategoryNeuroscience

Research Sub CategoryNeuronal & Glial MarkersSynapse & Synaptic Biology

Immunohistochemistry: 1:200-1:1,000

Optimal working dilutions must be determined by end user.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Arc/Arg3.1 is an immediate-early gene whose mRNA is rapidly transcribed and targeted to dendrites of neurons as they engage in information processing and storage. Arc/Arg3.1 is known to be required for durable forms of synaptic plasticity and learning. Arc/Arg3.1 has been shown to be expressed in neuronal cell bodies and dendrites in the brain regions including striatum and cortex hippocampus.

Immunogen

Synthetic peptide corresponding to a region within the C-terminus of human ARG3.1 protein.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Lyophilized. Reconstitute with 50 µL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.

Serum

Specificity

ARG3.1 [Growth factor ARC, Activity regulated cytoskeleton]

Storage and Stability

Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.