GLYCINE RECPT A3; RBX-100UG

Code: AB15014 D2-231

Application

Anti-Glycine Receptor α3 subunit Antibody detects level of Glycine Receptor α3 subunit & has been published & validated for use in IH & WB.

Immuno...


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€396.00 EACH
€487.08 inc. VAT

Application

Anti-Glycine Receptor α3 subunit Antibody detects level of Glycine Receptor α3 subunit & has been published & validated for use in IH & WB.

Immunohistochemistry Analysis: 1:100-500 dilution from a previous lot detected Glycine Receptor α3 subunit in mouse spinal cord and mouse eye tissue.

General description

Glycine receptor α3 subunit, also known as GLRA3, belongs to the ligand-gated ion channel family. Glycine functions as a inhibitory neurotransmitter throughout the CNS of mammals. The Glycine receptor is a neurotransmitter ligand-gated ion channel. GLRA3 is a pentamer that is composed of ligand binding alpha and structural beta subunits. When glycine binds to the receptor, chloride conductance increases which produces hyperpolarization. It is expressed in the hippocampus, olfactory bulb, and cerebellum. GLRA3 may be involved in human and murine neurological disorders.

Immunogen

This antibody is generated from rabbits immunized with a KLH conjugated linear peptide selected from residues surrounding the C-terminus of human Glycine Receptor α3 subunit.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH7.4) 150 mM NaCl with 0.05% sodium azide.

Format: Purified

Specificity

This antibody recognizes Glycine Receptor α3 subunit.

Rat (92%) homology.

Target description

Approx. 48 kDa

antibody formpurified antibody
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
Gene Informationhuman ... GLRA3(8001)
manufacturer/tradenameChemicon®
NCBI accession no.NP_006520.2
Quality Level100
shipped inwet ice
species reactivityhuman, mouse
technique(s)western blot: suitable, immunohistochemistry: suitable
UniProt accession no.O75311
This product has met the following criteria to qualify for the following awards:



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