Anti-Bovine Albumin (BSA)-Agarose antibody produced in rabbit, IgG fraction of antiserum, PBS suspension

Application

May be used for immunoprecipitation and immunoaffinity purification of Bovine Serum Albumin (BSA) from solutions.

Heparin-binding Merozoite antigens were detected by heparin-BSA binding assays using rabbit anti-BSAas the primary after plates were incubated with heparin-BSA on merozoite coated plates.

Rabbit Anti-Bovine Albumin (BSA)-Agarose antibody has been used as a negative control in several immunoassays.

Used for immunoprecipitation and immunoaffinity purification of BSA from solutions.Anti-Bovine Albumin (BSA)-Agarose antibody produced in rabbit has been used in mass spectrometry.

Biochem/physiol Actions

Serum albumin acts as a depot protein.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Serum albumins are soluble constituents of circulatory system. Bovine serum albumin (BSA) is homologous to human serum albumin (HSA). BSA consists of three homologous domains (I, II, III), that are separated into nine loops by disulfide bonds.

Rabbit polyclonal anti-Bovine Serum Albumin (BSA)–Agarose reacts with bovine albumin.

Albumin, the major protein produced by liver cells, represents more than half of the total protein content of human serum. Many other body fluids also contain albumin. Three major functions for serum albumin have been proposed: maintenance of osmotic pressure, transportation of a variety of substances and an endogenous source of amino acids. The primary sites of albumin degradation are not known, but the protein can be metabolized by almost every organ in the body. Determination of serum albumin levels is a widely used screening test in clinical medicine. A decrease in serum albumin levels may indicate disease states such as malnutrition, cirrhosis, nephrotic syndrome, diabetes, gastrointestinal and hepatic diseases, thermal burns and pulmonary disease.

Immunogen

purified BSA from Cohn Fraction V

Physical form

Suspension in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Preparation Note

Prepared by conjugating the IgG fraction of anti-bovine serum albumin (BSA) to cyanogen bromide-activated agarose.