Nitrotyrosine MagBead Conjugate

Analysis Note

ControlA431 whole cell lysate stimulated with 10 mM Peroxynitrite (5 minutes).

Application

Research CategorySignaling

Research Sub CategoryGeneral Post-translation Modification

Anti-Nitrotyrosine Magnetic Bead Conjugate Antibody is an antibody against Nitrotyrosine for use in IP.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Nitrotyrosine has been identified as an indicator of cell damage and inflammation, as well as of the production of NO. It is believed that measuring the concentration of nitrotyrosine will serve as a marker for damage caused by NO in the cell. Previous studies have shown that nitrotyrosine has been found in inflammatory conditions such as atherosclerotic plaques and rheumatoid arthritis, among others.

Immunogen

Nitrated KLH

Physical form

20% slurry; 1x PBS, 0.05% sodium aside.
Sufficient for 10 IPs.

Immunoaffinity Chromatography

Format: Purified

Quality

Evaluated by immunoprecipitation on A431 whole cell lysate stimulated with 10 mM Peroxynitrite (5 minutes).

Storage and Stability

Stable for 1 year at 2-8°C from date of shipment. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Target description

Varies