Analysis Note

ControlPositive Control Included: Jurkat cell lysate (12-303)

Application

Research CategorySignaling

Research Sub CategoryChromatin Biology

Anti-dimethyl-Arginine Antibody, symmetric (SYM10) is a high quality Rabbit Polyclonal Antibody for the detection of dimethyl-Arginine & has been validated in ICC, IP & WB.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Arginine methylation is a post-translational modification that results in the formation of asymmetrical and symmetrical dimethylated arginines (a- and sDMA).

Does not recognize non-methylated peptides, peptides containing asymmetrically dimethylated arginines, or a peptide containing a single symmetric dimethylarginine.

Immunogen

peptide containing four symmetrical dimethyl-arginine-glycine repeats

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Whole rabbit antiserum containing 0.05% sodium azide and 30% glycerol. Liquid at -20°C.

Quality

routinely evaluated by immunoblot in RIPA lysates from Jurkat cells

Specificity

Recognizes proteins that contain multiple symmetrically dimethylated arginines, including p80-Coilin and the Sm protein B, B′ and D.

Storage and Stability

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Target description

varies