Application

Research CategorySignaling

This Anti-TNFalpha Antibody, clone MPG-XT3 is validated for use in NEUT for the detection of TNFα.

Research Sub CategoryGrowth Factors & Receptors

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The concentration of antibody needed to neutralize the bioactivity of TNF-α will depend on the cell type, the incubation conditions, and the biological response studied.

Immunogen

Recombinant murine TNF-α

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 04-1114

Physical form

0.01M Tris-glycine, 0.15M NaCl, pH 7.4

Format: Purified

DEAE chromatography

Quality

routinely used to neutralize 50% of the cytotoxic effect of recombinant mouse TNF-α on actinomycin D treated L929 cells.

Specificity

mouse TNF-α; does not recognize human or rat TNF-α

Storage and Stability

2 years at -20°C

Target description

17 kDa