Application

Research CategoryProtein Trafficking

Research Sub CategoryUbiquitin & Ubiquitin Metabolism

Detect 19S regulator non-ATPase subunit S5a/Rpn10 using this Anti-19S regulator non-ATPase subunit S5a/Rpn10 Antibody, clone S5a-18 validated for use in IP & WB.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Rpn10 (S5a) is a non-ATPase subunit of the 19S regulatory complex of the 26s proteasome. Subunit Rpn10 (S5a) of the 26S proteasome was originally identified as a protein capable of binding poly-ubiquitin chains of four or more ubiquitins, in the absence of other 26S proteasome subunits.

Immunogen

Full length human recombinant Rpn10 protein.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

100 µL of purified immunoglobulin in PBS containing 0.01M sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4.

Format: Purified

Specificity

Recognizes 19S regulator non-ATPase subunit S5a/Rpn10.

Storage and Stability

Stable for 1 year at -20°C from date of shipment for up to 12 months.

Target description

41 kDa