Artesunate, from Artemisia annua

Code: A3731-500MG D2-231

Biochem/physiol Actions

Artesunate acts on the electron transport chain, generates local reactive oxygen species, and causes the depolarization of the mitochondrial membrane....


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Your Price
€627.00 500MG
€771.21 inc. VAT

Biochem/physiol Actions

Artesunate acts on the electron transport chain, generates local reactive oxygen species, and causes the depolarization of the mitochondrial membrane. It inhibits TNFα-induced production of proinflammatory cytokines via inhibition of NF-κB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes.

General description

Artesunate is a semisynthetic derivative of artemisinin used to treat malaria. It has also been shown to effective against other parasites such as liver flukes. Artesunate also demonstrates cytotoxic action against cancer cell lines of different tumor types.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Packaging

100, 500 mg in poly bottle

antibiotic activity spectrumneoplastics, parasites
biological sourceArtemisia annua
colorwhite to off-white
formcrystalline powder
InChI keyFIHJKUPKCHIPAT-JQXDXKTESA-N
InChI1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18?,19-/m1/s1
mode of actionprotein synthesis | interferes
Quality Level100
solubilityacetone: 33.4 mg/mL
storage temp.room temp
Cas Number88495-63-0
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