26430-5G Display Image

Chlortetracycline hydrochloride, suitable for fluorescence, BioReagent, from Streptomyces aureofaciens, >=97.0% (AT)

Code: 26430-5G D2-231

Application

Cell-permeable fluorescent probe for Ca2+ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ.


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€49.70 5G
€61.13 inc. VAT
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Application

Cell-permeable fluorescent probe for Ca2+ for measuring calcium flux in endoplasmic reticulum and other intracellular stores in situ.

Biochem/physiol Actions

Chlortetracycline is an antibiotic produced by some strains of Streptomyces aureofaciens.Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-positive. Less active against Gram-negative bacteria than tetracycline.Mode of Resistance: Loss of cell wall permeability.

General description

Chemical structure: tetracycline

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Packaging

5 g, 25 g, 100g

Quality

Recommended for fluorescent studies of calcium signaling in cells or tissues.

antibiotic activity spectrumGram-positive bacteria, Gram-negative bacteria
assay≥85.0% (HPLC)
biological sourceStreptomyces aureofaciens
colorfaintly yellow to yellow
fluorescenceλex 392 nm; λem 536 nm in 0.1 M Tris pH 8.0, 10 mM Ca2+
formpowder or crystals
InChI keyCBHYYLPALVVVEY-LYNLVHCPSA-N
InChI1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7?,8-,15-,21-,22-;/m0./s1
mode of actionprotein synthesis | interferes
mp210-215 °C (dec.) (lit.)
product lineBioReagent
Quality Level200
SMILES stringCl.CN(C)[C@H]1[C@@H]2CC3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c4c(O)ccc(Cl)c4[C@@]3(C)O
solubilityH2O: 50 mg/mL
storage temp.−20°C
suitabilitysuitable for fluorescence
Cas Number64-72-2
This product has met the following criteria: