KCC-07

Code: SML2547-25MG D2-231

Biochem/physiol Actions

KCC-07 is a brain penetrant, potent and selective inhibitor of MBD2 (methyl-CpG-binding domain protein 2) that inhibits binding of MBD2 to methylated ...


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€377.90 25MG
€464.82 inc. VAT
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Biochem/physiol Actions

KCC-07 is a brain penetrant, potent and selective inhibitor of MBD2 (methyl-CpG-binding domain protein 2) that inhibits binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling. KCC-07 inhibits medulloblastoma cell proliferation, and inhibits tumor growth in mice xenograft models of medulloblastoma.

assay≥98% (HPLC)
colorwhite to beige
formpowder
SMILES stringOC1=CC(NC2=NC(C3=NC=CC=C3)=CS2)=CC=C1
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
Cas Number315702-75-1
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