SR-4995

Code: SML2207-5MG D2-231

Biochem/physiol Actions

SR-4995 is a potent and selective ligand of α-β-hydrolase domain containing 5 (ABHD5) that activates adipose triglyceride lipase (ATGL) by d...


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€93.17 5MG
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Biochem/physiol Actions

SR-4995 is a potent and selective ligand of α-β-hydrolase domain containing 5 (ABHD5) that activates adipose triglyceride lipase (ATGL) by dissociating ABHD5 from its inhibitory regulator, perilipin-1 (PLIN1) and PLIN5. SR-4995 directly binds to ABHD5 and prevents ABHD5 to PLIN1. SR-4995 induces lipolysis in adipocytes and muscle, avoiding PKA-dependent signaling.

assay≥98% (HPLC)
colorwhite to beige
formpowder
SMILES stringCN1C(C(C=CC=C2)=C2SC3=C1C=C(NC(NCCCC)=O)C=C3)=O
solubilityDMSO: 2 mg/mL, clear
storage temp.−20°C
Cas Number891509-95-8
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