METFORMIN HYDROCHLORIDE EUROPEAN PHARMA

Code: M0605000 D2-231

Biochem/physiol Actions

Metformin is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition...


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Biochem/physiol Actions

Metformin is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.

Caution

Please find SDS provided by EDQM here..

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

agencyEP Reference standard
application(s)pharmaceutical (small molecule)
formatneat
gradepharmaceutical primary standard
InChI keyOETHQSJEHLVLGH-UHFFFAOYSA-N
InChI1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
manufacturer/tradenameEDQM
mp223-226 °C (lit.)
SMILES stringCl[H].CN(C)C(=N)NC(N)=N
Cas Number1115-70-4
This product has met the following criteria to qualify for the following awards:



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